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Neosil

Neosil is a privately-held dermatology-focused specialty pharmaceutical company with several products in pre-clinical development. The company’s core topical anti-infective technology provides broad anti-microbial activity, long duration of activity, and excellent formulation flexibility. The technology is based on the work of polymer chemist Dr. Samuel P. Sawan, a Professor in the Department of Chemistry at the University of Massachusetts, Lowell. Neosil was incubated and initially funded by Shalon Ventures with follow-on financing provided by MPM Capital (www.mpmcapital.com) and Burrill and Co. (www.burrillandco.com).


OsteoGenix

Osteogenix is a therapeutic products company with novel products for the large and rapidly growing area of bone repair and bone growth. Osteogenix was founded in 2005 to clinically develop and commercialize the osteo-pharmacologic platform discovered and patented by Dr. Mundy and his associates. Osteogenix assembled an outstanding team of expert advisors, many of whom have been principal investigators in key orthobiologics trials.


iWhisper

iWhisper is an excess weight reduction company, developing a discreet, lightweight, and wearable device that helps users lose weight and keep it off. iWhisper monitors how users actually eat – notably the timing, duration, and speed of eating – and provides real-time feedback to help them change their eating habits. The device is connected to the iWhisper Network, which tracks progress and enables the user and device to automatically communicate with their clinician or peer group, thereby increasing compliance and efficacy. Completely noninvasive and easy to use, iWhisper represents a revolutionary and disruptive approach to the treatment of obesity, one of the largest unsolved medical problems today.


AirXpanders

AirXpanders is developing a next generation tissue expansion platform for use in reconstructive surgery and burn treatment. AirXpanders was co-founded by Dr. Dan Jacobs, a leading reconstructive surgeon at Kaiser Permanente in the San Francisco Bay Area. Dr. Jacobs brought to Shalon Ventures his desire for a more effective and more automated tissue expander. Shalon Ventures provided the technical and business know-how to address this unmet medical need.


Synteni

Synteni pioneered the use of DNA microarrays for the genomic revolution. Starting with an academic research project, Shalon Ventures developed Synteni into one of the leading genomic players and service providers in four years. Two years after its founding, Shalon Ventures obtained follow-on funding for Synteni from Kleiner Perkins Caulfield and Byers (www.kpcb.com), with Brook Byers joining the Synteni Board of Directors. Synteni was acquired in 1999 by Incyte (NASDAQ: INCY).


BioPolymerix

In collaboration with Sam Sawan PhD, a Professor of Chemistry at the University of Massachusetts, BioPolymerix developed a silver-based antimicrobial coating for medical applications. These proprietary coatings prevent infection and biofilm formation on a wide range of implantable medical devices. BioPolymerix was acquired by Biocompatibles International.


Intelligent Biocides

Using BioPolymerix’s silver technology platform, Intelligent Biocides developed a broad set of anti-microbial products for the consumer industry.